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KMID : 0882420160900040361
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Korean Journal of Medicine
2016 Volume.90 No. 4 p.361 ~ p.364
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Healthcare-associated Endocarditis by PVL-negative ST 72 SCCmec Type IV MRSA
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오혜미:Oh Hye-Mi
김경엽:Kim Kyung-Up/박소연:Park So-Yeon/이진서:Lee Jin-Seo/김재석:Kim Jae-Seok/엄중식:Eom Joong-Sik
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Abstract
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The prevalence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been increasing worldwide. In Korea, the most common genotype of CA-MRSA is the Panton-Valentine leukocidin-negative, sequence type 72 Staphylococcal cassette chromosome (SCC) mec type IV clone. However, within Korean hospitals, this strain is still not commonly reported. In this study, we describe a case of infective endocarditis caused by Panton-Valentine leukocidin-negative MRSA (ST72-SCCmec type IV A clone). Infection occurred after open reduction and internal fixation due to a right humerus fracture with cerebral hemorrhage. Initially, the patient was treated with linezolid, but with the onset of severe thrombocytopenia, the patient was switched to vancomycin therapy.
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KEYWORD
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Methicillin-resistant staphylococcus aureus, Endocarditis, Linezolid
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